Structural & Molecular Biology

Computational Approaches in Structural Biology

Computational Biology includes most of the aspects bioinformatics. It is the science of using biological data to develop algorithms or models to understand among various biological systems and relationships. There are approximately more than 3.3 million sequences without structure. This gap in the structural knowledge can be bridged by computation. Computational biology has become an important part of developing emerging technologies for the field of biology. Identification of suitable template of the related protein family plays a major role. Computational structural biology or structural bioinformatics is concerned with the analysis, simulation and prediction of the structure, dynamics and interactions of large biomolecules such as proteins, DNA and RNA. Such systems push the limits of our understanding and the limits of computing power.